What Prescription Diet Pills Are Available – For decades, doctors have sought the dream of every dieter: a pill that can shed pounds without harm.
Their quest to accept that weight loss and self-care is not just a matter of wishful thinking, of refusing the siren call of the ice cream in the fridge.
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New research has shown that weight gain changes the brain and body. And even if we starve ourselves, we often cannot reverse these changes. So we slowly pack the pounds back on because our mind thinks we need them.
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In the early 1990s, doctors thought they had struck gold with a combination of drugs, fenfluramine and phentermine, or fen-phen, which seemed to magically dissolve fat. But within a few years, some patients began to have very dire consequences: damage to the heart valves that could lead to heart failure and a form of high blood pressure, pulmonary hypertension, which proved fatal in some cases.
The Food and Drug Administration urged drugmakers to pull fenfluramine — the active ingredient in the formulation — which they did. The media that followed would scare patients away from diet pills for years – the fear continues today.
But with America getting fatter every year — two-thirds of Americans are now overweight or obese — doctors felt they had no choice but to continue their search for a safe, modest drug that would help patients lose weight. pound and release them.
The latest generation of drugs appears to do just that. They won’t make the obese model thin, but they will shave off excess fat to improve the risk of heart conditions such as high blood pressure, high blood sugar and high cholesterol, experts say.
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Take lorcaserin for example. Researchers found that this drug can lead to permanent weight loss of more than 5 percent in about 40 percent of patients at risk of heart attack, stroke, and death from heart disease without increasing the chance of such events. published report. recently in the New England Journal of Medicine.
The new study followed participants for three years. “Most of the early weight loss studies followed patients for one year, and some for up to two years,” said the study’s lead author, Dr. Erin Bohula, an assistant professor of medicine at Harvard Medical School and a cardiologist and researcher at the TIMI Study Group at Brigham and Women’s Hospital in Boston. “The problem with lifestyle interventions is that patients often lose weight first and then the weight is regained, sometimes more than the initial weight. So the problem is that it stays there for a long time.”
Food and Drug Administration campus in Silver Spring, Maryland October 14, 2015. Andrew Harnik/AP File
Although 5 percent of weight loss does not seem like a lot, “that is when there is a significant reduction in the risk of diabetes,” said Dr. Louis Aronne, professor of electrical research at Weill Cornell Medicine. “A loss of 5 percent of weight is associated with a 50 percent reduced risk of diabetes, and a 10 percent loss is associated with an 80 percent reduced risk.”
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People need to be aware that in the treatment of obesity, just as in the treatment of hypertension, one drug does not fit all, Aronne said. “In hypertension, there are more than 100 drugs and more than 10 treatment groups,” he added. “That’s why the treatment of hypertension is effective. There is no cure for high blood pressure that works for everyone. That is where we should start looking at obesity drugs. “
What many people don’t understand is that weight gain leads to changes in the brain that may not be reversible, Aronne said. “Being overweight makes it difficult to lose weight,” he explained, adding that in some areas of the brain, neurons become damaged and sometimes die.
Eisai Belviq drug, which can help people lose weight and keep it off for several years without increasing the risk of heart problems, according to a new study. Eisai via AP
This new understanding is why some major medical institutions have deemed diet pills essential in the fight against obesity.
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Weight-loss medications are recommended in addition to diet and exercise — including, for example, in 2013 guidelines from the American Heart Association, the American College of Cardiology and the Obesity Society, Bohula said. But it’s still “low usage.” There are several other reasons for this, including cost, if not covered, and the assumption that these drugs are not historically safe for weight loss. “
In fact, a 2017 report that reviewed the medical records of 2.2 million patients found that fewer than one in 50 patients eligible for a prescription for a diet pill received one.
It is not surprising that Dr. Vijaya Surampudi, an endocrinologist and assistant professor of medicine at the Center for Human Nutrition at the University of California, Los Angeles. “I always advise them,” he said. “But they are not very popular.” I don’t think many doctors are comfortable prescribing diet pills. Fen-phen scares most of them. “
When it comes to eating, Americans need to rethink how they view weight, Surampudi said. “People need to focus on good health,” he said. “Instead of thinking about how good you’ll look in this dress, you should think, ‘I don’t have diabetes now.’
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Other than that, a little patience goes a long way. “We didn’t gain weight overnight,” said Surampudi. “And we shouldn’t expect it to come out overnight.” Fact: losing weight is hard. That’s why we turn to products that promise it won’t be bad—you can still eat what you want or skip your workout and wake up slimmer the next day. That idea sells: In 2015, the U.S. weight-loss industry was a $65 billion business, according to research firm Marketdata, and food and weight-loss products accounted for half of that. The problem is that some of these things are too good to be true, and the worst part is that they can be very harmful. Here are 10 you shouldn’t try.
If you keep up with the Kardashians, Klan-Khloe isn’t shy about sharing Insta photos of her favorite high heels. Proponents of the corset-shaped device say it sucks you in around the middle, and some brands even make you look up to three sizes smaller. Now we’re not saying it won’t happen – eventually it might. But Charlie Seltzer, M.D., a weight loss doctor and representative of the American Board of Obesity Medicine, says if you follow the idea of wearing them for hours at a time, you’re in trouble. Waist trainers put pressure on your organs and can interfere with breathing, affect the digestive tract and cause reflux. “The average person isn’t going to die from waist trainers – you’ll be fine if you wear them for a short period of time – but the argument that they’ll build muscle or push fat out has zero science,” he says.
Also called water pills, taking them helps remove sodium and water from the body and is mainly used to treat health problems such as high blood pressure. But using them to lose weight quickly is a no-no, as they can be dangerous without a doctor’s advice, says Charles Nguyen, MD, director of Lorphen Medical Weight Loss Clinic in Riverside, Calif., and co-author
. “You can get really dehydrated and damage your kidneys,” he says. “They can also interact with other drugs and cause an overdose.” If that’s not enough to convince you, remember that you’re only losing water weight. The next time you drink or eat something, you get it all back. “If you lose three pounds because you’re dehydrated, how will that help you in the long run?” Nguyen asks. You are right.
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So you need to lose weight – and fast. Throw on one of these warm clothes—or a trash bag over your sweats if you go the DIY route—strengthen your heart, sweat a ton, and voila! You will lose a few pounds. Unfortunately, you’re at risk for dehydration and low blood pressure from the heat, and those at risk for kidney problems (which tend to be overweight adults) can develop non-organ complications, says Seltzer. On top of that, “people do it to lose a few pounds, but I think they know deep down that they can’t lose that much fat in one day,” he says. Passport.
Companies claim that caffeine boosts your metabolism and has fat-burning magic (not to mention great reproductive performance). And studies even show that extra caffeine can help you burn about 100 extra calories a day. But at the end of the day, they don’t matter. “The more caffeine you consume, the greater the risk of side effects such as anxiety, rapid heart rate and sleep problems,” says Nguyen. Although you can drink a lot
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