What Diet Pills Work Best – When it comes to weight loss, there is no shortage of weight loss pills, drinks and supplements. But do weight loss pills help and are they safe?
The best weight loss pills may contain one or more active ingredients designed to increase fat burning, decrease appetite, or decrease fat absorption.
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Not all weight loss pills and supplements are created equal. Some pills can cause unpleasant side effects, while others have not been proven to cause weight loss.
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Before choosing a weight loss pill, it is important to do thorough research as some may have side effects or interact with existing conditions.
Alli is the brand name for the drug orlistat. It is one of the most popular weight loss pills.
Orlistat is available as a prescription medicine and is available over the counter. It prevents the body from breaking down some of the fats that people eat. Weight loss can occur when the intestines absorb less fat.
Orlistat has been shown to increase weight loss in small amounts. The study found that those who took orlistat lost an average of 2.9 percent more weight than those who did not take the drug.
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Orlistat may cause changes in bowel habits. People taking Orlistat may experience side effects such as diarrhea, abdominal pain, and difficulty controlling bowel movements.
Caffeine is a stimulant found in coffee, tea, soft drinks and chocolate. It is also often added to diet pills and supplements.
Among 76 overweight adults, those who consumed the most caffeine experienced greater reductions in fat mass, waist circumference, and total weight than those who consumed the least amount of caffeine.
Glucomannan is a type of fiber supplement. It works by absorbing water in the gut, creating a feeling of fullness that can encourage people to eat less.
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However, a recent review of randomized control trials found that glucomannan does not cause significant weight loss.
Garcinia cambogia extract contains the juice of this small fruit and is available as a weight loss pill. Garcinia cambogia can inhibit or prevent a fat-producing enzyme called citric acid lyase.
There is very little scientific evidence to support the use of this extract to aid in weight loss. According to
Although garcinia cambogia extract does not promote weight loss, it does not cause many side effects when taken in reasonable doses. The above report also indicated that no side effects occurred at dietary doses of up to 2,800 milligrams (mg) per day.
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The body produces pyruvate when it breaks down sugar. Pyruvate is also marketed as a supplement that helps with weight loss by breaking down fat and increasing metabolism.
, pyruvate may have some effect on weight loss. The available research is weak, so the results are inconclusive.
Many diet pills contain green tea because it can increase the body’s ability to burn fat, especially fat in the abdominal area.
Although more evidence is needed, some studies suggest that drinks containing green tea extract may help lose belly fat. An increased fat loss can also lead to a small weight loss.
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Conjugated linoleic acid is a type of fatty acid found mainly in beef and dairy products. Marketed as one of the best weight loss pills with the potential to increase metabolism and suppress appetite.
However, most studies on conjugated linoleic acid for weight loss have been conducted on animals. According to
Conjugated linoleic acid appears to be safe for up to 12 months at doses up to 6 grams per day. Possible side effects include stomach upset, diarrhea or constipation. May not be suitable for people with diabetes.
Hydroxycut is a popular dietary supplement. There are different Hydroxycut products that contain different ingredients. Hydroxycut products usually contain herbal extracts and caffeine, but caffeine-free versions of the supplement are also available.
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There are no studies specifically looking at Hydroxycut. Studies have shown that caffeine can contribute to weight loss in small amounts.
Because the ingredients in Hydroxycut vary, it is difficult to say which side effects may occur. Hydroxide supplements that contain caffeine can cause jitteriness and increase heart rate.
Hydroxycut is a supplement and is not tested as rigorously as drugs to determine its safety.
Some weight loss pills are only available with a doctor’s prescription. Although there are a variety of pills on the market, most weight loss medications work by making dietary fat more difficult to absorb or by suppressing appetite.
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Prescription pills can cause weight loss, but they can have side effects. Depending on the prescription, side effects of weight loss pills may include abdominal pain, dry mouth, and diarrhea.
When it comes to the best weight loss pills, there seems to be no magic bullet. Although some of the diet pills and supplements mentioned above can contribute to weight loss, the amounts are usually modest.
Some diet pills can also cause side effects, the most common being stomach discomfort and changes in bowel movements.
Dietary supplements do not undergo the same scrutiny as drugs approved by the United States Food and Drug Administration (FDA), so their safety is not always fully understood. Before taking a weight loss supplement, it is best to speak with a doctor or other health professional.
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For people trying to lose weight, the best options are to reduce portion sizes, eat lean protein and vegetables, and exercise regularly.
Medical News Today has strict guidelines for purchasing and sources only peer-reviewed studies, academic research institutes, medical journals and associations. We do not use third party links. We link to primary sources in each article, including studies, scientific references and statistics, and list them in the sources section at the bottom of our articles. You can learn more about how we ensure our content is accurate and up-to-date by reading our editorial policy. LA JOLLA – Scientists have developed an entirely new type of pill that tricks the body into burning fat by tricking it into thinking it has consumed calories. The compound effectively halted weight gain, lowered cholesterol, controlled blood sugar and minimized inflammation in mice, making it an excellent candidate for fast-track human clinical trials.
Unlike most diet pills on the market, this new pill, called fexaramine, does not dissolve in the blood like appetite suppressants or caffeine-based diet pills, but stays in the intestines and causes fewer side effects.
Ronald Evans, director of the Gene Expression Laboratory, developed a compound called fexaramine that acts as a phantom food. Fexaramine, which tricks the body into responding as if it has consumed calories, could lead to effective treatment of obesity and diabetes in humans.
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“This pill is like a fantasy meal,” says Ronald Evans, director of the Gene Expression Laboratory and senior author of a new paper published Jan. 5, 2015, in the journal Nature Medicine. “It sends the same signals that normally happen when you eat a lot of food, so the body starts freeing up space to store it. But there are no calories and the appetite does not change.
According to the Centers for Disease Control and Prevention, more than one-third of adults in the United States are obese, and 29.1 million people have diabetes. Both obesity and diabetes lead to increased healthcare costs, increased risk of health complications and reduced life expectancy.
Researchers at the institute have developed a fat-burning compound called fexaramine that causes weight loss in animal models without the usual side effects. Fexaramine tricks the body into responding as if it has consumed calories and may lead to effective treatment of type 2 diabetes and obesity in humans.
Evans’ lab has spent nearly two decades studying the farnesoid X receptor (FXR), a protein that plays a role in how the body removes bile acids from the liver, digests food, and stores fat and sugar. The human body turns on FXR at the beginning of a meal, Evans et al have shown, in preparation for the influx of food. FXR not only triggers the release of bile acids for digestion, but also changes blood sugar levels and causes the body to burn some fat in preparation for food.
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In order to treat obesity, diabetes, liver disease and other metabolic diseases, pharmaceutical companies have developed systemic drugs that activate FXR and activate many of the pathways that FXR controls. But these drugs affect multiple organs and come with side effects. Evans wondered if turning on FXR in just the gut, rather than the gut, liver, kidney and adrenal glands all at once, might produce a different result.
Researchers have shown that fexaramine inhibits weight gain and burns fat in animal models. Fexaramine is only absorbed in the intestine and does not enter the bloodstream, so it does not cause side effects common to regular diet pills. After further testing, researchers believe this will lead to an effective weight loss treatment for people with diabetes.
“When you eat, you quickly activate a series of responses throughout your body,” says Evans. “And the truth is, the first responder to all of this
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