Prescription Diet Pills Cost – Today, with the arrival of diet pills in pharmacies, there are two new prescription drugs for the treatment of obesity – the first new drugs available for seriously ill patients in more than a decade. The drug offers a 5% to 10% increase in weight loss, but has become another “tool in the toolbox” for doctors trying to rid America of its obesity crisis.
Starting today, Belviq (pronounced bel-VEEK) sold by Eisai will be available in pharmacies. It works on brain chemistry to create a feeling of fullness and can help obese patients lose about 5% or more of their initial weight when used with a calorie-reduced diet and exercise.
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The wholesale cost of a month’s supply of Belvic to pharmacies is less than $200, said Gary Palmer, Eisai’s chief medical officer. The price patients pay depends on their insurance coverage and can vary between pharmacies, he said. “We see many options for patients who do not have insurance (belviq.com) and need financial support for their treatment.”
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Another new diet drug from Vivus, Qsymia (pronounced kyoo-SIM-ee-uh), released in mid-September, helps overweight people lose about 10% of their weight by suppressing their appetite and increasing the feeling of fullness.
Both drugs are designed to treat overweight patients who are obese, meaning they weigh more than 35 pounds, or have other weight-related conditions, such as high blood pressure, type 2 diabetes, or high cholesterol. . About one third of people in this country are obese. The drug is not intended for people who want to lose a few pounds for cosmetic reasons.
Initial sales of Qsymia were lower than the company expected, but demand is growing and coverage is improving, said Vivus senior vice president Michael Miller.
About 89,000 prescriptions were written for Qsymia since its introduction through March, he said. For those paying cash, the drug costs about $150 a month. About a third of patients have a $50 co-pay with their insurance company’s prescription, Miller said. The company offers free medicine for the first two weeks, and a 50% discount on the first month of treatment, he said.
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A new anti-obesity drug was approved by the Food and Drug Administration last summer. These drugs are a new “tool in the toolbox” for doctors treating obese patients, said Harvey Grill, president of the Obesity Society and professor of behavioral neurology at the University of Pennsylvania. Several other new anti-obesity drugs are on the horizon, and others are currently being studied, he said.
Other diet drugs used to treat obesity include the appetite suppressant phentermine; and orlistat (Xenical), which prevents the absorption of some dietary fats through the intestine. Orlistat is sold as a low-dose, over-the-counter version as Alli.
Ben Jankowitz, 58, of Los Angeles, who has type 2 diabetes, has lost about 20 pounds since starting Qsymia a few months ago. At a height of six feet, he now weighs 185, down from 205. According to him, this drug really suppresses hunger. “Throughout the day, I have to remind myself to eat lunch,” says Jankowitz, CEO of California-based Proteus Energy.
Jankowitz says he hasn’t experienced any serious side effects from Qsymia, but it’s “not a magic pill. You have to exercise and follow a healthy diet,” he said.
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Patients also reported weight loss success in trials of Belviq, a drug that works by activating chemical receptors in the brain that help people eat less and feel full after eating smaller meals.
Lisa Sutter, 52, a city government worker in Washington, D.C., lost weight after taking Belvic for two years during one of the drug trials. At 5-foot-5, he dropped from 230 pounds to 190 pounds.
“Honestly, it’s easy. . . . Even though I only eat 1,600 calories a day, I don’t feel hungry.”
Sutter said he didn’t experience any side effects from the medication, but when he stopped taking it after the drug test was over, his hunger returned. He couldn’t stick to a low calorie diet and he put the weight back on and then some. Now that Belvic is on the market, he plans to return to it because “I know it’s working well for me.”
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However, there are concerns about the side effects and risks of both drugs. Sidney Wolfe, founder and senior adviser of the health research group at the consumer group Public Citizen, said: “We are strongly opposed to both. Both are in great danger.”
Belvic was rejected by an FDA advisory board in 2010 due to safety concerns. When the advisory committee met a second time, members discussed cardiovascular issues but decided the drug’s benefits outweighed the risks. The agency later approved the drug.
The product label warns: “Some people who take drugs like Belvic have heart valve problems. … Before taking Belvic, tell your doctor if you have or have had heart problems.
The drug’s manufacturer (Arena Pharmaceuticals) and marketer (Eisai) should conduct long-term cardiovascular trials to assess Belvic’s effect on the risk of serious cardiac events, such as heart attack and stroke, Palmer said.
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Wolff says Belvic “actually showed damage to the heart valve before it was approved. The risks of this drug far outweigh any benefits.”
He said that “magical thinking to believe that you can turn off something as complex as hunger without affecting various systems, especially the cardiovascular system.”
Said Palmer: “We have done a very long development program with Arena Pharmaceuticals, involving almost 8,000 patients studied for up to two years. In this program, we have seen no heart valve problems when used in appropriate patients. However, we will continue to monitor the efficacy and product safety.”
Some experts are concerned that Qsymia may slightly increase the heart rate in some patients. It consists of two other older drugs: the appetite suppressant phentermine and the anticonvulsant topiramate, sold under the brand name Topamax. The latter is used to treat epilepsy and migraines.
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Wolf fears that history will repeat itself. In 1997, two diet drugs were withdrawn from the market – fenfluramine (part of the popular phen-phen combination) and dexfenfluramine (Redux) – because, like Belvic, there was evidence of heart valve problems that occurred only after approval.
In 2010, Abbott Laboratories withdrew sibutramine (Meridia) from the market due to the increased risk of heart attack and stroke. The examples and viewpoints in this article relate mainly to the United States and do not reflect the views of the entire world on the subject. If necessary, you can improve this article, discuss the problem on the chat page or create a new article. (September 2020) (Learn how and why to delete this template message)
Orlistat (Xical), the drug most commonly used to treat obesity, and sibutramine (Meridia), were immediately withdrawn due to cardiovascular side effects.
Antiobesity drugs or weight loss drugs are pharmacological drugs that reduce or control weight. This drug changes one of the basic processes of the human body, by changing weight regulation, appetite, or caloric absorption.
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Diet (healthy eating and calorie restriction) and exercise remain the basis of treatment for overweight and obese people.
In the United States, orlistat (Xical) and semaglutide (Wegovy) are currently approved by the FDA for long-term use.
Xical reduces intestinal fat absorption by inhibiting pancreatic lipase; Wegovy is a GLP-1 analog, a class of drugs that holds promise as a relatively straightforward and effective anti-obesity measure.
Because of side effects and limited evidence for weight loss in obese children and adolescents,
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Anti-obesity medication is recommended for obesity only if the expected benefits of the treatment outweigh the risks.
In the United States, the Food and Drug Administration supports a body mass index of at least 30 or a body mass index of at least 27 for people with at least one weight-related comorbidity to restore the patie population. high basic health risk to justify the use of antiobesity medication.
Anorexics are mainly appetite suppressants, but many drugs in this class also act as stimulants (eg amphetamine), and patients have abused “unknown” appetite suppressants (eg digoxin).
The first described attempt to lose weight was the Greek physician Soran of Ephesus in the second century AD. He likes laxative and purgative elixirs, as well as heat, massage, and exercise. It has been a mainstay of healing for over a thousand years. Only in the 1920s and 1930s, new methods of treatment began to appear. Thyroid hormone has become a popular treatment for obesity in euthyroid individuals based on its effectiveness in hypothyroidism. It has a modest effect, but causes symptoms of hyperthyroidism, such as palpitations and difficulty sleeping. 2, 4-Dinitrophol (DNP) was introduced in 1933;
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