High Protein Diet Kidney Stones – Evaluation of the effect of dietary supplements on cognitive functions in healthy adolescents and military personnel.
Open Access Policy Institutional Open Access Program Specific Guidelines Guidelines Research Review and Publication Ethics Article Processing Fees Awards Reports.
High Protein Diet Kidney Stones
All articles published worldwide are now available under an open license. No special permission is required to reuse all or part of an article published by , including images and tables. For articles published under the Creative Common CC BY license, any part of the article may be reused without permission as long as the original article is clearly identified. For more information, see https:///openaccess.
Get Rid Of Kidney Stones With The Right Nutrition: Things You Need To Know
Feature articles present the best research with the greatest potential to make a big impact in this field. Abstracts are submitted at the invitation or recommendation of scientific editors and are subject to scientific review before publication.
The presentation can be an original research article, a large-scale study that often focuses on techniques or approaches, or a comprehensive review article with brief and factual reports on the topic. new work progress to systematically evaluate the most interesting scientific advances. document. This type of article provides an overview of future research directions or applications.
Editorial articles are created based on the recommendations of scientific journal editors from around the world. The editors select a small number of articles published in the journal that they believe are of particular interest to readers or important in any field of research. The aim is to provide a snapshot of some interesting papers published in the various research areas of the journal.
Andrea Ticinesi 1, 2, *, Antonio Nouvenne 1, 2, Giulia Chiussi 1, Giampiero Castaldo 1, Angela Guerra 1, 3 and Tiziana Meschi 1, 2, 3
Pdf] Dietary And Holistic Treatment Of Recurrent Calcium Oxalate Kidney Stones: Review Of Literature To Guide Patient Education.
Received: Jan 31, 2020 / Revised: Feb 14, 2020 / Accepted: Feb 18, 2020 / Published: Feb 20, 2020
Recent studies have shown that patients with kidney stones and calcium oxalate nephrolithiasis show dysbiosis of fecal and urinary microflora compared to controls. Alteration of the microbiota prior to the simple presence and presentation of Oxalobacter formigenes, a well-known indicator that has the potential to degrade dietary oxalate and stimulate oxalate secretion by the intestinal mucosa. Therefore, changes in the gut microbiota may play a role in the pathophysiology of calcium stones. However, the role of diet in this gut-renal axis is unknown, even if some foods such as poor hydration, high salt and protein intake are not known. pets and limiting fruit and vegetable consumption are risk factors for kidney stones. In this literature review, we provide an overview of the gut-kidney axis in nephrolithiasis from a nutritional perspective, summarizing the evidence supporting a role for diet in modulating microbiota composition and is associated with modulation of lithogenic risk.
The digestive system plays an important role in the pathophysiology of idiopathic calcium oxalate nephrolithiasis, the most common form of kidney cancer [1, 2, 3]. The absorption of the intestinal mucosa is closely related to the metabolism of calcium and oxalate and is the main cause of hypercalciuria and hyperoxaluria, two important prolithogenic urinary metabolic abnormalities found in calcium oxalate stones [4, 5, 6]. The terms “absorptive hypercalciuria” and “intestinal hyperoxaluria” indicate the presence of crosstalk between the stomach and kidneys, which contributes to the pathophysiology of calcium oxalate stones [4, 5, 6].
The role of intestinal microbial communities, or microflora, in these processes remained uncertain until a few years ago [7]. In fact, research has mainly focused on one part of the human gut microbiota, Oxalobacter formigenes [7]. The ability of this gram-negative anaerobic bacterium to break down oxalate has led to the conclusion that calcium oxalate nephrolithiasis is related to intestinal destruction by Oxalobacter [8]. On the contrary, probiotic activity with Oxalobacter or others Unfortunately, empirical research and gave conflicting results, leaving great doubts about the role of the microbiome in lithogenesis [7].
Types Of Foods You Shouldn’t Eat If You Have Kidney Disease
In the last decade, advanced omics technologies have enabled deep organization and characterization of the gut microbial community at an unprecedented level [11]. Therefore, the first physiological concept of the entero-renal axis in nephrolithiasis was wiped out in the light of the so-called. microbiome revolution [7]. Recent studies have shown that calcic stones have a different fecal microbiota than those without stones, supporting the hypothesis that the microbiome is important in the pathophysiology of kidney stones [7, 12, 13].
These studies shed light on the gut-kidney axis in kidney stones, but in most cases do not provide a link to kidney stone treatments and diet. Dietary factors such as poor hydration, high salt and animal protein content, and low intake of calcium, fruits and vegetables (FAV) are considered major risk factors for calcium oxalate urolithiasis [14, 15]. In contrast, hydration, adequate intake of dairy products, FAV, and low-fat protein foods are considered the pillars of kidney stone prevention [16, 17]. It is unclear how these clinical concepts are integrated with microbiome-focused acquisitions on the gut-kidney axis, although the recognition of food as determinants of gut microbiota composition.
The purpose of this literature review is to summarize the current knowledge on the relationship between the gut microbiome and calcium oxalate kidney stones from a nutritional perspective.
Oxalobacter formigenes was first isolated in 1980 from the rumen of some mammals and metabolically characterized as having a strong ability to degrade oxalate [18]. It is the most efficient oxalate-degrading biological system known to date, thanks to the expression of two enzymes, oxalyl-CoA decarboxylase and formyl-CoA transferase, which enable the production of soluble formate compounds and CO.
Proteinuria: Causes, Symptoms, Tests & Treatment
With the release of energy used by bacteria for cellular activities [19, 20]. In the following years, Oxalobacter was isolated from the intestines of some mammals, including humans, and was trained on substances rich in oxalate [21]. An inverse relationship between Oxalobacter in the intestinal lumen and oxalate absorption has also been reported in guinea pigs [22].
However, the role of Oxalobacter in kidney stone disease in humans was not further explored until the late 1990s, when a polymerase chain reaction (PCR) method was developed to detect and quantify Oxalobacter [23]. Oxalobacter is found in 30-70% of human samples and its presence is strongly associated with high dietary oxalate intake and low oxalate reduction [24]. Therefore, the role of Oxalobacter in lithogenic transformation was investigated. In fact, Oxalobacter may prevent kidney stones through two different mechanisms: reducing the amount of oxalate in the intestinal lumen along with reducing mucosal absorption, and promoting endogenous secretion of oxalate by the intestinal mucosa [25].
Observational studies conducted using culture-based and PCR-based methodology showed that the presence of Oxalobacter in fecal samples was very low in masons or patients with high lithogenicity than in non-focal controls (Table 1) [26, 27, 28, 29, 30. ]. For idiopathic stones, one study found a significant relationship between the degree of Oxalobacter colonization and urinary oxalate excretion within 24 hours [30], while another study did not [29]. This pattern was seen in people with kidney stones due to cystic fibrosis [26] or gastric ulcer [28], but not morbidly obese [31]. The relationship between colonization status and oxaluria may depend on dietary oxalate intake, which is particularly evident in experimental conditions with controlled dietary regimens [32].
Recent population studies combining traditional specific microbiology techniques with metagenomics have shown that Oxalobacter is present in the fecal microbiome of only 31% of healthy young adults living in the US [33]. This disease is less than that of the indigenous peoples of Venezuela and Tanzania, confirming the role of diet and lifestyle in creating Oxalobacter colonization [34]. In a large group of samples from the American Gut Project, the main factors affecting the presence of Oxalobacter in the gut microbiota were race, country of residence, age, education level, recent exposure to antibiotics, body weight, alcohol, and FAV drinking [35]. A healthy lifestyle and diet can positively influence the composition of the intestinal microflora colonized by Oxalobacter.
The Link Between Keto & Kidney Stones
Since the late 1990s, several intervention studies have investigated whether administration of Oxalobacter or other oxalate-reducing probiotic supplements may result in a reduction in lithogenic risk (Table 2) [36, 37, 38, 39, 40, 41, 42, 43]. All of these trials were conducted with a small number of participants (the largest included only 42) and varied in the nature and duration of the intervention and the types of treatment of the participants, from healthy volunteers to children with severe forms of primary hyperoxaluria. (Table 2). The results are generally conflicting, with some studies showing a significant reduction in urinary oxalate excretion after probiotic treatment [36, 37, 38, 40, 41, 42] and others showing no change from baseline [39, 43] (Table 2). The importance of reducing urinary oxalate excretion is unclear,
High protein diet and kidney stones, kidney stones prevention diet, oxalate kidney stones diet, diet for kidney stones, vegan diet kidney stones, can high protein diet cause kidney stones, does high protein diet cause kidney stones, kidney stones and diet, kidney stones diet restrictions, calcium kidney stones diet, protein and kidney stones, high protein diet cause kidney stones
