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Gluten Free Diet And Hypothyroidism

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Gluten Free Diet And Hypothyroidism

Gluten Free Diet And Hypothyroidism

The thyroid is a butterfly-shaped gland in the lower neck that produces hormones that regulate many body functions, including metabolism, heart rate, digestion, muscle control, brain development, mood regulation, and bone maintenance. This is very important for your overall function and well-being. In this case, more and more people have thyroid problems, including autoimmune thyroid disease (AITD), such as Hashimoto’s thyroiditis (autoimmune hypothyroidism) or Graves’ disease (autoimmune hyperthyroidism).

How Going Gluten Free Can Help With Hypothyroidism

AITD is an autoimmune condition in which the immune system destroys the thyroid gland. In this condition, the immune system attacks the thyroid gland. The thyroid should have homogeneous edges, which are round and smooth in this butterfly-shaped gland. In an inflamed state with AITD, the gland will often become enlarged. If AITD is not treated properly, it will cause the gland to be smaller than normal size, indicating atrophy. This process causes a decrease in the secretion of thyroid hormones, causing severe symptoms. Anything that increases the immune response against the thyroid will increase thyroid atrophy and destroy the thyroid faster.

To understand thyroid autoimmunity, it is also important to understand acquired immunity. Acquired immunity is an adaptive response of the immune system to pathogens and this is the reason for creating vaccines. When the immune system encounters a pathogen, the cells form a very specific response and remember the pathogen by identifying its antigen, so when it is found again, this response is intensified to destroy the pathogen. In the acquired immune system, pathogen-specific receptors are acquired throughout the life of the organism to mark and destroy invading pathogens. However, in the process, the immune system can have a wrong response where it reacts to its own tissue in this aggressive way.

One of the mechanisms that can cause this incorrect response is cellular mimicry, which is when the immune system marks both pathogens and innocent tissues in the body as one and the same and tries to destroy them both. This is the case in AITD. Although researchers are still working to discover why some people may be more susceptible to autoimmune diseases than others, we do know that risk factors may include:

You’ve probably heard that if you have AITD, it’s wise to eliminate gluten, and even dairy, from your diet. This can be hard to swallow for those of us who consider bread, milk and cheese staples in our diet. In this article, we discuss why gluten and dairy consumption can be a problem for those with AITD, and why gluten and dairy are inflammatory in general. In addition, we discuss other foods that can be problematic for the thyroid.

Hashimoto’s Disease: What To Eat For Better Management

Gluten is a protein in a variety of grains, including wheat, barley, and rye. Gluten contains a protein called gliadin, and the molecular structure of gliadin is very similar to transglutaminase – an enzyme found throughout the body to create chemical bonds. This enzyme is abundant in the gut and thyroid gland. If you have AITD, your body makes antibodies that attack transglutaminase in the thyroid gland. (1, 2)

When you eat gluten and the gut is exposed to gliadin, the gliadin leads to the upregulation of zonulin, which removes the tight junctions of the gut and increases intestinal permeability. This intestinal permeability occurs in ALL people, regardless of whether the person is sensitive to gluten or not (3). As intestinal permeability increases, gliadin can then pass through the intestinal barrier and into the bloodstream.

Because of the molecular structure of gliadin (4) like transglutaminase, the body can mark it in the bloodstream as a foreign invader to be attacked as well. This can then trigger your body in a heightened state to attack both gliadin and transglutaminase, an enzyme made in the thyroid gland, due to their structural similarity. In other words, whenever gliadin is in the bloodstream, the body can mount an immune response to gliadin and also attack the thyroid gland.

Gluten Free Diet And Hypothyroidism

Research has shown that eliminating gluten in AITD patients can significantly reduce thyroid antibody titers (5). Although we don’t know the exact percentage, studies have also shown that there is a correlation between AITD and celiac disease (CD), which is an autoimmune condition that causes damage to the intestines through gluten consumption. The incidence of CD is significantly increased in individuals with AITD. It is important to screen AITD patients for CD and CD patients for AITD (6, 7). Among those with AITD, an estimated 2-5% also have CD (8). The diagnosis of CD is most likely confirmed by genetic markers (HLA DQ2 or HLA DQ8) with biopsy. For the diagnosis of thyroid disease, see here.

Tips To Lower Your Thyroid Antibodies

We learned that one should not have CD suffering from the harmful effects of gluten. There is a lot of research documenting the inflammatory nature of gluten, including its ability to increase intestinal permeability and induce an inflammatory response, both in patients with and without CD. Increased intestinal permeability can lead to a number of chronic health conditions, including rheumatoid arthritis, multiple sclerosis, inflammatory bowel disease, asthma, chronic fatigue syndrome, and depression (9). As previously stated, intestinal permeability or leaky gut caused by gluten can also lead to AITD. When gliadin is able to penetrate the intestinal wall, the body has the potential to mark it as an invader and create antibodies for gliadin and thyroid due to their similar protein structure. In addition, with increased specificity and sensitivity in stool testing, we learned that more people are sensitive to gluten than previously believed (10).

For those with CD or AITD (or anyone with suspected non-celiac gluten sensitivity), it is very important to go completely gluten-free, as the effects of gluten consumption last up to six months. While those with non-celiac gluten sensitivity or CD may experience unpleasant digestive symptoms after consuming gluten, their thyroid health may also be compromised (12).

Another food that should be limited for people with AITD is dairy products. In AITD patients, lactose intolerance can also be a problem. In one study, Hashimoto’s patients who also tested positive for lactose intolerance significantly increased their TSH (thyroid-stimulating hormone) levels after eight weeks of lactose restriction (13).

Casein, a protein found in dairy products, is structurally very similar to gliadin, a protein in gluten. When your body reacts to gluten, there is a good chance that it may also react to dairy products because of this protein. If the body sees gliadin as a pathogen, there is a good chance that it can recognize casein as a pathogen as well due to their similar structure. In this case, it can stimulate the same immune response as caseins like gliadin. In one small study with patients with CD, about 50% of these patients had a similar inflammatory response to cow’s milk as gluten (14).

The Easy Thyroid Diet Plan: A 28 Day Meal Plan And 75 Recipes For Symptom Relief: Kyle Ms Rdn Clt Hcp, Emily: 9781646116652: Books

Milk also tends to be pro-inflammatory for many, mainly because of the sugar (lactose) and protein (casein and whey) found in it. People who have lactose intolerance cannot digest lactose, and it is estimated that as much as 65% of the human population is lactose intolerant (15).

Additionally, many struggle to digest the casein in milk, especially the A1-beta casein in milk, which has a similar protein structure to gliadin. In animal studies, digesting casein, especially the A1-beta casein found in conventional dairy products, can increase digestion time as well as the production of inflammatory markers compared to A2-beta casein milk. In humans, participants who consumed A2 milk compared to those who consumed A1 milk had significantly higher stool Bristol values ​​and less abdominal pain (16).

In another study, milk with A1-beta casein was associated with increased gastrointestinal inflammation, increased digestive discomfort, delayed transit, and decreased cognitive speed and accuracy, while A2 beta-casein did not produce these symptoms (17). However, when changing your diet, it is wise to first eliminate all casein from your diet if you are very sensitive to casein. Then you can try A2 milk from cows, goats or Jersey sheep to see if you can tolerate it.

Gluten Free Diet And Hypothyroidism

Clinically, it’s easy to see the benefits of going gluten-free and dairy-free if you have thyroid problems. In a clinical survey of 2,232 people with Hashimoto’s, 88% of those who switched to gluten felt better, 3.2% felt worse, and 33% reduced their thyroid antibodies. In the same sample, among those who stopped consuming dairy products, 79% felt better, 1.5% felt worse, and 20% had reduced thyroid antibodies (18).

Diet And Thyroid Disease

In another study of 38 patients with Hashimoto’s disease and lactose intolerance, after eliminating dairy products, 75% of patients had reduced thyroid stimulating hormone levels.

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Sarah Hi I'm Sarah, I like to write anything about health, healthy food and other health tips. Healthy living has become a necessity in this day and age, where the body needs good nutrition. Hopefully my writing can be useful for all.

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